I was very disappointed when Gel-Kayano 15 debuted. I was a fan of prior versions, but not the 15 and I blogged about the reasons why https://drshoe.wordpress.com/2009/01/15/shoe-review-gel-kayano-15-vs-14/. The main difference was the 15 was deeper than the 14 and the 15 was much more unstable laterally. These trends haven’t changed with Gel-Kayano 16.
Overall, Gel-Kayano 16 is not a big departure from the 15 with the exception that it is even deeper. The medial midsole of the 15 and 16 are nearly identical as shown below. The outsole is exactly the same.
Gel-Kayano 16 has a similar midsole to the Gel Kayano 15 with more gel and less EVA in the lateral (outside) midsole. This design may make your heel strike more wobbly causing things like ankle sprains or tendonitis. Everyone doesn’t necessarily need firm lateral EVA but if you do, you would be better off with the 2150 than the Gel Kayano 15. This modification is a huge departure from versions 14 and prior.
Asics has continued with the asymmetrical lacing, however this version design is better than the the 15. I’m still not a fan of asymmetrical lacing, but at least this one won’t bunch up causing irritation like the 15 did. The lack of trim over the big toe, also means less potential irritation along the top of the big toe.
The one plus is Gel-Kayano 16 has a higher heel counter int he back which will reduce heel slippage if that’s been a problem for you.
Overall, Gel-Kayano 16 is too much like Gel-Kayano 15 and not enough like Gel-Kayano 14 and prior versions for me to recommend.